Updating emission computed tomography in neuropsychiatry

• Updating emission computed tomography in neuropsychiatry - Thesis 1993 - abdel elhameed,amany haroun elrasheed

المؤلف

abdel elhameed,amany haroun elrasheed

العنوان

ubdating emission computed tomography in neuropsychiatry بيان المسئولية : amany haroun elrasheed abdel elhameed;abdel elmoneim mahmoud ashour,mohammed anwar eltribi

عنوان موازي

التحديث في إستخدام المسح المقطعي للدماغ بالكمبيوتر بإستخدام النظائر المشعة في مجال الأمراض العصبية و الطب النفسي

تاريخ النشر

1993 الحجم: 320p;. ابعاد الوعاء: 26cm

درجة الرسالة

thesis(m.d)-ain shams university.faculty of medicine

ملخص

UPDATING EMISSION COMPUTED TOMOGRAPHY IN NEUROPSYCHIATRY

The advent of functional imaging has revolutionized the capacity to understand both nor1:1al and abnormai brain h:nc:ior .. Of the currently available tec..:.\niques, PET is t~.e :nos: :r..:or:r.a.L-:e beca:J.se i~ a~lov .. ;s accurate quantification of cerebral blood r1ov~~ ar~d rr.eta1Jojs::-. and ~cas super:or spatial :-esolution \\rhen compared to SPECT. As 2. C.icec: c:.::-.seq:.:ence of ::Ce ~r.trod:.:ctiocc. of PET a:ld SPECT technologyl’ significant adva:~.ces ~a\·e bee~. ::--.ade L.1. ou:r k.LO\,~ledge of conditions a incl~..:de cere”brovasc:.:.la:- C..iso:-C.ers, .:1ea;:: :~.11.:.:-:es. o:-a::i. t:..:::-.c;.J:-s, nove!:le!l: d:sorders academically interesting but also clir.icaJ:y rele’.’an:. So, this thesis ai:ned to re\·ie·.,· the ::::r:pac: of these techniques on understanding ci:ffere:tt neurolog:ca: a~.d ::-:3vc:-::ar:-:c disorde:-s and their manage:ner.t. EITJssion corr~vuted torrtog;a::;!v .. - :J:’O\.·eC to ’:)e useful in the foilov..ri_.;.a0

.. ’- J. - .. • TIAs whe:!’. CT and :VlRI are ::s’-’C2.:lv :1egc.t>:2 a:1C. helps identiiying those at • SAH as SPECT faciiitc.tes ea~:v diagnosis of ce~e’Jral hypoperbsion C.::e to {’ • Aiso in Sturge -Weber Syndrome, AVM and neuropsychiatric SLE. • In head trauma it helps to demonstrate the widespread cerebral dysfunction which correlates wih the degree of clinical impairment. In cerebral turr10urs it is helpful i..”l.: - The prediction of the grade of malignancy and its prognosis. - The differentiation betv.•een recurrent tun10urs and radiation necrosis. Measuring the uptake of antineoolastic drugs and measuring its tumor killing pote!l:ials. • Distinguishing some of the var:ous cat:ses of movement disorders that are otherwise d:ffic:.llt to difieyen:iate. • Ea:-ly detec:Oor. of HD in patier.ts at risk, i.e. hav:ng positive family history and helps to diagnose patients v,it~ ty?ical clinical fear . .rres but an unclear family histor::. • In epileptic patients wit:C u:cconc:-oEec seizu~es oi pe,-s=ec ~ocal origin who a:-e candidates £or epile?SY surge!}·· • Early detection of dementia ami d:fie,-entiating AD fror:c L’”te following:-

• ~ormal pressure hydrocephal:.rs
• De:nentia d”..le to frontal :abe degeneration and subcortical dementias
• Depressive pseudoCeme:ttia

• In psychoactive substance use disorders, it helps to sru.dy changes in CMR and CBF d1.:ring ac.2te ar.d c:Cronic ir,toxication as well as during Vvithdrawa!. • In schizophrenic patients, r:-,ost of tr.e studies had demonstrated hypofrontality whic..’”t has beer: acibuteC. to eiL’”ter chronicity or e:xposure to neuroleptics. However, other areas of hypometabolism or hypoperfusion had been der:1onstrated depending on the subtype and syrnptoms. Also, cha..”lges in dopaminergic receptor binding in the basal ganglia have been found whiG’l are modified on treatment. However, the following disorders require considerably more research as relatively few are done and to define whether consistent abnormalities are prese.”lt or not: - DernyelinatL.’”lg disorder-s. - Encephalitis - Movement disorders - Some psychiatric disorders as: • Psyc...~oactive st:bstar:.ce :.:se C.:sorC.ers • 5~1-t.izoohre...”l.ias • Affective disorder-s • Neurotic disorders • Autisn • Stutter’~.g

مؤلف فرعي

el tribi,mohammed anwar / editor مؤلف فرعي: ashour,abdel elmoneim mahmoud / editor

الهيئة المشرفة

ain shams university / faculty of medicine